WebApr 11, 2024 · FTH1 expression in the OEFTH1 group was considerably increased (Figure 6A and B). Furthermore, as compared with the ESC group, the expression of the yellow spots and red fluorescent NCOA4 were substantially decreased in the OEFTH1 and ESC combined group ( Figure 6C and D ), demonstrating that esculetin causes ferritinophagy … WebMar 21, 2024 · ACSL4 (Acyl-CoA Synthetase Long Chain Family Member 4) is a Protein Coding gene. Diseases associated with ACSL4 include Intellectual Developmental Disorder, X-Linked 63 and Stroke, Ischemic.Among its related pathways are Fatty acid metabolism and Integration of energy metabolism.Gene Ontology (GO) annotations related to this …
Full article: Inhibitory Effects of Esculetin on Liver Cancer Through ...
WebFeb 20, 2024 · H-ferritin (FTH1) is essential for mammalians’ development, as the full knock-out of its gene leads to embryonic death in mice 9. FTH1 differs from L-ferritin (FTL) ... WebMay 9, 2024 · Tetrandrine citrate (TetC), a novel tetrandrine salt with high water solubility, demonstrates a potent antitumor activity in chronic myeloid leukemia. Studies have indicated an important role of ferroptosis in breast cancer (BC). However, whether TetC inhibits BC progression via ferroptosis has never been explored. In the present study, we showed … jon harris christian
FTH1 Gene - GeneCards FRIH Protein FRIH Antibody
WebApr 5, 2024 · A critical role of a FTH1 gene:pseudogene:miRNA network in regulating tumorigenesis in prostate cancer, whereby oncogenic miRNAs downregulate the expression of FTH1 and its pseudogenes to drive oncogenesis. Data show that piR-FTH1 (ferritin heavy chain 1) knocks down the Fth1 mRNA via the HIWI2 and HILI mediated mechanism. WebApr 14, 2024 · Ferritin is composed of 24 subunits of FTH1 and FTL (Park and Chung, 2024). NCOA4 has been reported to bind FTH1 at the phagophore and is delivered into the lysosome for degradation to release iron, a process known as ferritinophagy (Mancias et al., 2015). To further elucidate the molecular mechanisms for baicalin-generated decrease in … WebNational Center for Biotechnology Information jon harris christian author