Major facilitator superfamily 是什么
Web16 feb. 2024 · The major facilitator superfamily is one of the largest secondary transporter families found on Earth, consisting of sub-families harboring homologous and related solute-specific transport systems [ 11, 13 ]. Multidrug efflux pumps that are members of the major facilitator superfamily can contribute to drug resistance in many … Web23 jul. 2024 · 基因超家族(Gene Superfamily): 同一个祖先基因经过变异,产生了结构相似、功能 不同 的各种表达蛋白,表达这些蛋白的基因统归为一个基因超家族。 如肿瘤坏死因子(tumor necrosis factor,TNF)超家族成员,大家都有TNF同源结构域,但功能上有的成员诱导细胞凋亡(如FasL),有的成员促进细胞增殖、发育、分化(如LT-α、LT-β), …
Major facilitator superfamily 是什么
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Web1 mrt. 2013 · The evolutionary origins of the major facilitator superfamily of secondary carriers are probed, providing evidence that they arose from a single 2‐transmembrane segment (TMS) hairpin structure that triplicated to give a 6‐TMS unit that duplicated to a 12 TMS protein, the most frequent topological type of these permeases. 402 PDF http://html.rhhz.net/SWJSTB/html/2024-8-43.htm
Web20 feb. 2024 · 基因超家族(Gene Superfamily): 同一个祖先基因经过变异,产生了结构相似、功能 不同 的各种表达蛋白,表达这些蛋白的基因统归为一个基因超家族。 如肿瘤坏死因子(tumor necrosis factor,TNF)超家族成员,大家都有TNF同源结构域,但功能上有的成员诱导细胞凋亡(如FasL),有的成员促进细胞增殖、发育、分化(如LT-α、LT … WebInterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
WebMajor facilitator superfamily domain containing 2a (Mfsd2a)is a sodium-dependent lysophosphatidylcholine (LPC) transporter. The endothelium of the micro vessels in blood brain barrier express high levels of Mfsd2a. Immunogen. MFSD2A antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MFSD2A. Web14 sep. 2024 · (rs5888), and major facilitator superfamily domain containing the 2a (MFSD2A) (rs12083239, rs4233508, rs12072037) on the relationship between circulating lipids in aging subjects with T2DM.
Web13 jan. 2016 · Members of the major facilitator superfamily are highly conserved transmembrane proteins that transport various small molecules, including nutrients, …
Web1 jan. 2015 · The ancient and ubiquitous major facilitator superfamily (MFS) represents the largest secondary transporter family and plays a crucial role in a multitude of … orion boat houseWeb6 jan. 2024 · Purpose:The major facilitator superfamily (MFS) is known as the largest and most diverse superfamily containing human transporters, and these transporters are … how to write a short story tipsWebThe major facilitator superfamily (MFS) is one of the two largest families of membrane transporters found on Earth. It is present ubiquitously in bacteria, archaea, and eukarya … orion boatworks facebookWeb28 mei 2024 · CcoA belongs to the widely distributed bacterial copper (Cu) importer subfamily CalT (CcoA-like Transporters) of the Major Facilitator Superfamily (MFS), and provides cytoplasmic Cu needed for cbb 3-type cytochrome c oxidase ( cbb 3-Cox) biogenesis. Earlier studies have supported a 12 transmembrane helices (TMH) topology … orion boats the hull truthWebThe major facilitator superfamily (MFS) is one of the largest groups of secondary active transporters conserved from bacteria to humans. MFS proteins selectively transport … orion boat house restaurantWebThe ancient and ubiquitous major facilitator superfamily (MFS) represents the largest secondary transporter family and plays a crucial role in a multitude of physiological processes. MFS proteins transport a broad spectrum of ions and solutes across membranes via facilitated diffusion, symport, or antiport. how to write a short story templateWeb17 dec. 2024 · A multidrug efflux pump designated LmrS (lincomycin resistance protein of Staphylococcus aureus), belonging to the major facilitator superfamily (MFS) of transporters, was cloned, and the role of LmrS in antimicrobial efflux was evaluated. The highest relative increase in MIC, 16-fold, was observed for linezolid and … how to write a short story for beginners