WebNational Center for Biotechnology Information WebMay 9, 2024 · Knockdown of MYBL2 was obviously reversed the roles of miR-423-5p in apoptosis and mitochondrial dysfunction. Taken together, miR-423-5p suppression reduced H/R-induced cardiomyocytes injury through activation of the wnt/β-catenin signaling pathway via targeting MYBL2 in cardiomyocytes. CONFLICT OF INTERESTS
Overexpression of MYBL2 predicts poor prognosis and promotes ...
WebMar 4, 2024 · Wnt signaling inhibition induces a BRCA-like state; and Wnt and PARP inhibitors synergize to inhibit Wnt-addicted cancers. Wnt signaling regulates the … WebJan 12, 2011 · Recent results from our laboratory 18 showed that Mybl2 expression and activation are under genetic control in rodent hepatocarcinogenesis. Indeed, Mybl2 up-regulation was associated with faster growth and progression of premalignant and malignant liver lesions both in chemically treated rats and in a transgenic mouse model. good to be alive lyrics andy grammer
MYBL2 is a substrate of GSK3-like kinase BIN2 and …
WebTo activate Wnt signaling, one can add Wnt protein, either in a purified form or as conditioned medium to cells. Cells producing active Wnt can be obtained from the ATCC (see also the reagents page ). Active Wnt protein can be obtained from several companies. WebMar 21, 2024 · MYB Proto-Oncogene Like 2 (MYBL2) is a highly conserved member of the Myb family of transcription factors and plays a critical role in regulating cell proliferation and survival. Here we show that overexpression of MYBL2 is frequently observed in lung adenocarcinoma (LUAD) and significantly correlates with advanced stage and poor … WebA possible mechanism by which a R3-MYB protein might inhibit a particular pathway involves competition with R2R3-MYB for interaction with a bHLH protein, which results in … good to be alive pvris lyrics