Sensitisation - skin - category 1
WebSkin Sensitization Category 1 Specific target organ toxicity (single exposure) Category 3 Target Organs - Respiratory system. ... Kidney, Liver. Corrosive to metals Category 1 _____ Page 1 / 8 _____ Potassium hexachloroplatinate(IV) Revision Date 24-Dec-2024 Hazard Statements May be corrosive to metals Toxic if swallowed May cause an allergic ... Web1% can still be relevant for classifying the mixture for acute toxicity.1 b) The acute toxicity estimate (ATE) for an ingredient in a mixture is derived using: • The LD 50/LC 50 where available, 1 this is particularly relevant in the case of ingredients classified in Category 1 and Category 2. No Yes Sufficient data available on similar
Sensitisation - skin - category 1
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Webassays addressing other key events of the skin sensitisation AOP as well as non-testing methods, including read-across from chemical analogues. 9. The test method described in this Test Guideline can be used to support the discrimination between skin sensitisers (i.e., UN GHS Category 1) and non-sensitisers in the context of IATA. This Test ... WebThe Key Event 3/1 Sequential Testing Strategy is a sequential testing strategy that predicts skin sensitization hazard and GHS potency category. Predictions are based on the …
WebSkin irritation , Category 2 H315 : Causes skin irritation. Eye irritation , Category 2 H319 : Causes serious eye irritation. Skin sensitisation , Category 1 H317 : May cause an allergic skin reaction. Long-term (chronic) aquatic hazard, Cat-egory 2 H411 : Toxic to aquatic life with long lasting effects. 2.2 Label elements Labelling (SANS 10234)
WebSubstances shall be classified as contact sensitisers (Category 1) in accordance with the criteria given below: • if there is evidence in humans that the substance can induce … WebSkin sensitisation (Category 1), H317 Short-term (acute) aquatic hazard (Category 2), H401 For the full text of the H-Statements mentioned in this Section, see Section 16. 2.2 GHS Label elements, including precautionary statements Pictogram Signal word Danger .
Web19 assays addressing other key events of the skin sensitisation AOP as well as non-testing methods, including read-across from chemical20 analogues. 21 9. The test method described in this Test Guideline can be used to support the discrimination between skin 22 sensitisers (i.e., UN GHS Category 1) and non-sensitisers in the context of IATA.
WebFor instance, for a product classified in category 1/1B for skin sensitisation, the lowest in-use dilution (most concentrated) must be <1% (1:100). For a product classified in … goldilocks and the three bears poemWebThe Key Event 3/1 Sequential Testing Strategy is a sequential testing strategy that predicts skin sensitization hazard and GHS potency category. Predictions are based on the minimum induction threshold from the human cell line activation test (h-CLAT) and hazard results from the direct peptide reactivity assay (DPRA). goldilocks and the three bears pictureWebSensitisation of the respiratory tract or the skin Germ cell mutagenicity Carcinogenicity Reproductive toxicity Additional category for effects on or via lactation No Signal ... Skin. Sens. 1 Warning H317 May cause an allergic skin reaction Category 1 and Muta. 1, 1A or Danger H340 May cause genetic defects (4) Sub-Categories 1B Category 2 Muta ... head coach of rocketsWebA footnote related to respiratory sensitisation and skin sensitisation in Table 1.5.1 -a was removed. A correction to Example D, sub -chapter 4.1.4.7.5 was applied, name ly a reference to CLP, Annex I, point (b) (ii) of Table 4.1.0 was introduced. In addition the result of a summation method calculation was corrected. Version 4.1 head coach of penn stateWebHC092:Skin sensitisation – category 1] to [HC092:Skin sensitisation – category 1] Pictogram modified from [GHS06] to [GHS07] Hazard Statement modified from [H330 Fatal if inhaled; H301 Toxic if swallowed; H311 Toxic in contact with skin; H317 May cause an allergic skin reaction] to head coach of sacramento kingsWebSkin sensitization, sometimes referred to as allergic contact dermatitis (ACD), is considered to be one of the largest causes of occupational injury in the USA.84 It often develops as a … goldilocks and the three bears pop up bookWebFor example, if ingredients of a mixture lead to classification both as respiratory sensitisation category 1 (Resp. Sens. 1) and respiratory sensitisation sub-category 1A … goldilocks and the three bears powerpoint