2024 Sulf1 ovary

Sulf1 ovary

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Web1 May 2024 · Some previous pertinent studies reported that SULF1 was dysregulated in many cancers, such as ovarian cancer, hepatocellular cancer and breast cancer [ 19 - 22 ], and was undetected in A2780 and SKOV3, but it could be detected in normal ovarian cell lines (IOSE80) [ 23 ]. WebOvary OVARY - Expression summary The protein expression bar, with the units none (n), low (l), medium (m) and high (h), is based on a best estimate of the "true" protein expression …

Polymorphisms in the SULF1 gene are associated with early age

Web7 Jan 2011 · SULF1 (sulfatase 1) selectively removes the 6-O-sulphate group from heparan sulfate, changing the binding sites for extracellular growth factors. SULF1expression has been reported to be decreased in various cancers, including ovarian cancer. Web21 Mar 2024 · SULF1 (Sulfatase 1) is a Protein Coding gene. Diseases associated with SULF1 include Mesomelia-Synostoses Syndrome and Hepatocellular Carcinoma . Gene … the idea of working from home

Protein structure - SULF1 - The Human Protein Atlas

Web1 May 2024 · Lots of studies had demonstrated that SULF1 was associated with platinum resistance. Down-regulation of SULF1 in ovarian cancer cells led to an attenuation of … Web15 May 2024 · To decipher SULF1’s role in the reactive bone stroma, we created a bone marrow biomimetic hydrogel incorporating perlecan, PCa cells, macrophages, and fibroblastic bone marrow stromal cells. ... , with the majority showing reduced levels of SULF1 in progressive ovarian, hepatocellular, breast, and head and neck carcinomas ... Web28 Oct 2010 · Using Northern blot analysis, Lai et al. (2003) found that SULF1 was expressed in all normal ovarian surface epithelial cells examined, but it was weakly expressed or … the idea of university pdf

Sulf1 and Sulf2 expression in the nervous system and its …

Web10 Dec 2013 · The survey about polymorphisms of SULF1 gene, for the first time was performed by Han et al. who genotyped five common single nucleotide polymorphisms (SNPs) in SULF1 gene to evaluate associations between these functional SULF1 SNPs and the risk of ovarian cancer . They found that some of the SULF1 gene SNPs can have one … Web26 Aug 2024 · The reported impact of SULF1 on cancer progression is less consistent. Widespread low expression of the SULF1 transcript is observed in cancer cell lines 20,21 and prior studies suggested a tumor suppressor function … the idea of using a net came from which sporthttp://www.cancerindex.org/geneweb/SULF1.htm the idea of the uselessness of study

"WebProtein structure - SULF1 - The Human Protein Atlas DISEASE SULF1 PROTEIN STRUCTURE ANTIBODIES AND VALIDATION Protein structures PROTEIN STRUCTUREi Predicted Your browser/graphics card does not seem to support WebGL. Find out how to get it here. Description: Structure prediction from Alphafold project. Structure version 2 " - Sulf1 ovary

Sulf1 ovary

SULF1 SNP information, effects on age of disease onset, survival, …

WebThis study aims to develop a machine learning model incorporating genomic data such as Single-Nucleotide Polymorphisms (SNPs) of Human Sulfatase 1 (SULF1) with a CT … WebSULF1 is part of cluster 15 Smooth muscle cells - Muscle contraction with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated …

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Web21 Mar 2024 · SULF2 (Sulfatase 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include calcium ion binding and arylsulfatase activity . An important paralog of this gene is SULF1. UniProtKB/Swiss-Prot Summary for SULF2 Gene Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. Web* P < 0.05. from publication: Polymorphism in the SULF1 gene are associated with early age of onset and survival of ovarian cancer SULF1 (sulfatase 1) selectively removes the 6-O-sulphate group ...

http://www.cancerindex.org/geneweb/SULF1.htm WebSULF1 controls the sulfation status of heparan sulfate proteoglycans and plays a role in tumor growth and metastasis, while its role is unexplored in UC. To first elucidate the …

Web7 Jan 2011 · Background: SULF1 (sulfatase 1) selectively removes the 6-O-sulphate group from heparan sulfate, changing the binding sites for extracellular growth factors. SULF1 expression has been reported to be decreased in various cancers, including ovarian cancer. We hypothesized that single nucleotide polymorphisms (SNPs) of SULF1 would impact … Web1 May 2024 · Six candidate genes had been screened out including one previously validated gene SULF1 and five novel genes ZNF587B, TADA1, SEMA4G, POTEC and USP17L20. …

Web15 Jan 2024 · Sulf1 inhibits ISC division during normal homeostasis. ... In addition, it has been shown that JAK-STAT signaling is regulated by HSPGs in the ovary (Hayashi et al., 2012). Therefore, it is reasonable to speculate that Sulf1 also regulates this pathway.

WebGeneral description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene … the idea of using radioWebOvarian cancer is the leading cause of death from gynecologic cancers, but platinum resistance remains a major obstacle in the chemotherapy of ovarian cancer. This study aims to examine the role of polymorphisms in sulfatase 1 (SULF1) in platinum resistance and the idea of you by amanda prowseWeb1 Mar 2012 · SULF1 is an endosulfatase able to cleave specific 6-O sulfate groups within the heparan chains. This action can modulate signaling processes, modulating the effects of … the idea of university john henry newmanWebTo test whether the two CAF subtypes were a general feature of ovarian cancer stroma, we analyzed the gene expression dataset generated by Leung et al. (2014), who used laser … the idea of velcro was given byWebThis gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate gro ups from heparan sulfate chains of heparan sulfate … the idea of vegan come fromWeb23 Oct 2006 · In addition, research by other laboratories has shown that Sulf1 activity in ovarian cells decreases Noggin (a BMP antagonist) binding to the cell surface and hence enhances the activity of BMPs (Viviano et al., 2004), … the idea of you dave matthewsWeb1 Feb 2024 · SULF1 transcript is downregulated in ovarian, breast, kidney, pancreatic and hepatocellular cancer cell lines and primary ovarian tumors [ 16 ]. The lower expression level of SULF1 transcript was also observed in lung cancer cell … the idea of 什么意思